Abstract

Background: The Addenbrooke's Cognitive Examination-Revised (ACE-R) scale is used to assess cognitive impairment in clinical practice and research. This study obtained normative data associated with demographic characteristics using the Korean version of the ACE-R (K-ACER).

Methods: The K-ACER was administered to a normative study group comprising 722 healthy middleaged and older community-dwelling adults representative of the age and education level distribution within the Korean population. The obtained datawere analyzed with respect to demographic variables, including age, sex, and education levels.

Results: The mean (standard deviation) age in the overall study population and proportion of male participants (n = 329) were 60.3 ± 8.1 years and 45.6%, respectively. Themean K-ACER score was 80.7 ± 13.2 points. Older age and a lower educational level were associated with lower K-ACER scores. Subdivided percentile norms were calculated in the sub-analyses after age and education level stratification, which significantly affected K-ACER scores. Based on these findings, we determined normative data according to age and educational level.

Conclusions: Used with the detailed normative data we obtained, the K-ACER is a reliable, standardized instrument for screening and follow-up cognitive examinations.